Bibliographic Details
| Title: |
FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity |
| Authors: |
Vijayashree Mysore, Xavier Cullere, Joseph Mears, Florencia Rosetti, Koshu Okubo, Pei X. Liew, Fan Zhang, Iris Madera-Salcedo, Frank Rosenbauer, Richard M. Stone, Jon C. Aster, Ulrich H. von Andrian, Andrew H. Lichtman, Soumya Raychaudhuri, Tanya N. Mayadas |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Neutrophils are versatile immune cells that may also serve as antigen-presenting cells (APC). Here the authors show that engaging FcγRs on neutrophils with immune complexes or an anti-FcγR-antigen conjugate induces neutrophil APC with comparable functions as classical dendritic cells, and with therapeutic potentials for cancer and infectious diseases. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-24591-x |
| Access URL: |
https://doaj.org/article/86a5a1c6c18f436081a1927c18c8de2d |
| Accession Number: |
edsdoj.86a5a1c6c18f436081a1927c18c8de2d |
| Database: |
Directory of Open Access Journals |
