Bibliographic Details
| Title: |
The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors |
| Authors: |
Lina Liu, Ana Vujovic, Nandan P. Deshpande, Shashank Sathe, Govardhan Anande, He Tian Tony Chen, Joshua Xu, Mark D. Minden, Gene W. Yeo, Ashwin Unnikrishnan, Kristin J. Hope, Yu Lu |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Leukemic stem cells (LSCs) drive chemoresistance and relapse in acute myeloid leukemia. Here, the authors show that the splicing factor RBM17 supports LSCs through avoiding nonsense-mediated decay of pro-leukaemic factors such as the translation initiation factor EIF4A2. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-31155-0 |
| Access URL: |
https://doaj.org/article/85c36ded2db34489ade4dbffb3dc816b |
| Accession Number: |
edsdoj.85c36ded2db34489ade4dbffb3dc816b |
| Database: |
Directory of Open Access Journals |
