MRI evaluation of Pacinian corpuscle number and distribution in the forefoot in diabetic sensorimotor polyneuropathy

Bibliographic Details
Title: MRI evaluation of Pacinian corpuscle number and distribution in the forefoot in diabetic sensorimotor polyneuropathy
Authors: Sophia S. Goller, Georg C. Feuerriegel, Adrian A. Marth, Christoph Germann, Martin Schubert, Michèle Hubli, Felix W. A. Waibel, Reto Sutter
Source: Insights into Imaging, Vol 16, Iss 1, Pp 1-11 (2025)
Publisher Information: SpringerOpen, 2025.
Publication Year: 2025
Collection: LCC:Medical physics. Medical radiology. Nuclear medicine
Subject Terms: Pacinian corpuscle, MRI, Diabetes, Diabetic sensorimotor polyneuropathy, Medical physics. Medical radiology. Nuclear medicine, R895-920
More Details: Abstract Objectives To evaluate Pacinian corpuscles (PC) in the forefoot of patients with type 2 diabetes-derived sensorimotor polyneuropathy (DSP) with MRI. Materials and methods This single-center study compared 20 DSP patients who underwent clinical forefoot 3-T MRI to healthy volunteers matched for age and gender. Two radiologists independently assessed the number and distribution of PC. In addition, one radiologist determined PC size. Correlations between PC number, duration of diabetes, and Hemoglobin A1c (HbA1c) were assessed. Results In DSP patients, the number of PC in the forefoot was significantly reduced compared to healthy volunteers (82.7 ± 46.1 vs. 265.3 ± 49.3, p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1869-4101
Relation: https://doaj.org/toc/1869-4101
DOI: 10.1186/s13244-025-01932-8
Access URL: https://doaj.org/article/d85250429bc24e4796025176b4e568f6
Accession Number: edsdoj.85250429bc24e4796025176b4e568f6
Database: Directory of Open Access Journals
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More Details
ISSN:18694101
DOI:10.1186/s13244-025-01932-8
Published in:Insights into Imaging
Language:English