DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Bibliographic Details
Title: DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
Authors: Julien M. D. Legrand, Ai-Leen Chan, Hue M. La, Fernando J. Rossello, Minna-Liisa Änkö, Frances V. Fuller-Pace, Robin M. Hobbs
Source: Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Publisher Information: Nature Portfolio, 2019.
Publication Year: 2019
Collection: LCC:Science
Subject Terms: Science
More Details: Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA processing and export.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-019-09972-7
Access URL: https://doaj.org/article/852498ee4d314917b02f782d466e190b
Accession Number: edsdoj.852498ee4d314917b02f782d466e190b
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-019-09972-7
Published in:Nature Communications
Language:English