Reliability of Heterochromatic Flicker Photometry in Measuring Macular Pigment Optical Density among Preadolescent Children

Bibliographic Details
Title: Reliability of Heterochromatic Flicker Photometry in Measuring Macular Pigment Optical Density among Preadolescent Children
Authors: Sasha M. McCorkle, Lauren B. Raine, Billy R. Hammond, Lisa Renzi-Hammond, Charles H. Hillman, Naiman A. Khan
Source: Foods, Vol 4, Iss 4, Pp 594-604 (2015)
Publisher Information: MDPI AG, 2015.
Publication Year: 2015
Collection: LCC:Chemical technology
Subject Terms: macular pigment optical density, heterochromatic flicker photometry, retinal lutein, Chemical technology, TP1-1185
More Details: Macular pigment optical density (MPOD)—assessed using customized heterochromatic flicker photometry (cHFP)—is related to better cognition and brain lutein among adults. However, the reliability of MPOD assessed by cHFP has not been investigated in children. We assessed inter-session reliability of MPOD using modified cHFP. 7–10-year-olds (n = 66) underwent cHFP over 2 visits using 11 examiners. Reliability was also assessed in a subsample (n = 46) with only 2 examiners. Among all participants, there was no significant difference between the two sessions (p = 0.59—session 1: 0.61 ± 0.28; session 2: 0.62 ± 0.27). There was no significant difference in the MPOD of boys vs. girls (p = 0.56). There was a significant correlation between sessions (Y = 0.52x + 0.31; R2 = 0.29, p ≤ 0.005), with a reliability of 0.70 (Cronbach’s α). Among the subsample with 2 examiners, there was a significant correlation between sessions (Y = 0.54x + 0.31; R2 = 0.32, p < 0.005), with a reliability of 0.72 (Cronbach’s α). In conclusion, there is moderate reliability for modified cHFP to measure MPOD in preadolescents. These findings provide support for future studies aiming to conduct noninvasive assessments of retinal xanthophylls and study their association with cognition during childhood.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2304-8158
Relation: http://www.mdpi.com/2304-8158/4/4/594; https://doaj.org/toc/2304-8158
DOI: 10.3390/foods4040594
Access URL: https://doaj.org/article/8503d49ca4fd4633a7b091fcdee420c4
Accession Number: edsdoj.8503d49ca4fd4633a7b091fcdee420c4
Database: Directory of Open Access Journals
More Details
ISSN:23048158
DOI:10.3390/foods4040594
Published in:Foods
Language:English