Pervasiveness of intronless genes expressed in haploid germ cell differentiation

Bibliographic Details
Title: Pervasiveness of intronless genes expressed in haploid germ cell differentiation
Authors: Hiromitsu Tanaka, Akira Tsujimura
Source: Reproductive Medicine and Biology, Vol 20, Iss 3, Pp 255-259 (2021)
Publisher Information: Wiley, 2021.
Publication Year: 2021
Collection: LCC:Diseases of the endocrine glands. Clinical endocrinology
LCC:Reproduction
Subject Terms: chromosome, meiosis, retrotransposition, sperm, testis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Reproduction, QH471-489
More Details: Abstract Background cDNA libraries derived from the brain and testis contain genes that encode almost all proteins. The brain is composed of various differentiated cells, and the testis also contains various differentiated cells, such as germ cells, and somatic cells that support germ cell differentiation, such as Sertoli and Leydig cells. Many genes appear to be expressed due to tissue complexity. Methods The Genome Project has sequenced the entire genomes of humans and mice. Recent research using new gene analysis technologies has found that many genes are expressed specifically in male germ cells. Main findings (Results) Functional intronless genes are significantly enriched in haploid germ cellā€specific genes. Conclusion Functional intronless genes associated with fertility are more likely to be inherited in haploid germ cells than in somatic cells.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1447-0578
1445-5781
Relation: https://doaj.org/toc/1445-5781; https://doaj.org/toc/1447-0578
DOI: 10.1002/rmb2.12385
Access URL: https://doaj.org/article/a84d36d7dc7a492c9893149f80094c32
Accession Number: edsdoj.84d36d7dc7a492c9893149f80094c32
Database: Directory of Open Access Journals
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More Details
ISSN:14470578
14455781
DOI:10.1002/rmb2.12385
Published in:Reproductive Medicine and Biology
Language:English