Bibliographic Details
| Title: |
Smoking history and breast cancer risk by pathological subtype: MCC-Spain study |
| Authors: |
Belén Peñalver-Argüeso, Esther García-Esquinas, Adela Castelló, Nerea Fernández de Larrea-Baz, Gemma Castaño-Vinyals, Pilar Amiano, Tania Fernández-Villa, Marcela Guevara, Guillermo Fernández-Tardón, Juan Alguacil, Mireia Obón-Santacana, Inés Gómez-Acebo, Marina Pinto-Carbó, Rafael Marcos-Gragera, Nuria Aragonés, Amaia Aizpurua, Vicente Martín-Sánchez, Eva Ardanaz, Trinidad Dierssen-Sotos, Jose Juan Jiménez-Moleón, Manolis Kogevinas, Marina Pollán, Beatriz Pérez-Gómez |
| Source: |
Tobacco Induced Diseases, Vol 21, Iss November, Pp 1-16 (2023) |
| Publisher Information: |
European Publishing, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Diseases of the respiratory system
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
breast cancer, smoking, obesity, hormone receptor, her2, Diseases of the respiratory system, RC705-779, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Introduction The role of cigarette smoking on breast cancer risk remains controversial, due to its dual carcinogenic-antiestrogenic action. Methods In the population-based multi-case-control study (MCC-Spain), we collected epidemiological and clinical information for 1733 breast cancer cases and 1903 controls, including smoking exposure. The association with breast cancer, overall, by pathological subtype and menopausal status, was assessed using logistic and multinomial regression models. Results Smokers had higher risk of premenopausal breast cancer, particularly if they had smoked ≥30 years (AOR=1.75; 95% CI: 1.04–2.94), although most estimates did not achieve statistical significance. In contrast, among postmenopausal women, smoking was associated with lower risk of breast cancer, mainly in overweight and obese women. The strongest risk reductions were observed among postmenopausal women who had stopped smoking ≥10 years before cancer diagnosis, particularly for HER2+ tumors (AOR=0.28; 95% CI: 0.11–0.68); p for heterogeneity = 0.040). Also, those who had smoked |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1617-9625 |
| Relation: |
http://www.tobaccoinduceddiseases.org/Smoking-history-and-breast-cancer-risk-by-pathological-subtype-MCC-Spain-study,174132,0,2.html; https://doaj.org/toc/1617-9625 |
| DOI: |
10.18332/tid/174132 |
| Access URL: |
https://doaj.org/article/846928bbed6649129a3f7a1075e0dbe3 |
| Accession Number: |
edsdoj.846928bbed6649129a3f7a1075e0dbe3 |
| Database: |
Directory of Open Access Journals |
