Diagnosis and antibiotic therapy of nosocomial pneumonia in adults: from recommendations to real practice. A review
| Title: | Diagnosis and antibiotic therapy of nosocomial pneumonia in adults: from recommendations to real practice. A review |
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| Authors: | Svetlana А. Rachina, Ludmila V. Fedina, Marina V. Sukhorukova, Igor N. Sychev, Egor S. Larin, Abdulbari A. Alkhlavov |
| Source: | Терапевтический архив, Vol 95, Iss 11, Pp 996-1003 (2023) |
| Publisher Information: | "Consilium Medicum" Publishing house, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Medicine |
| Subject Terms: | nosocomial pneumonia, ventilator-associated pneumonia, antibiotics, microbiological diagnosis, Medicine |
| More Details: | Nosocomial pneumonia is a healthcare-associated infection with significant consequences for the patient and the healthcare system. The efficacy of treatment significantly depends on the timeliness and adequacy of the antibiotic therapy regimen. The growth of resistance of gram-negative pathogens of nosocomial pneumonia to antimicrobial agents increases the risk of prescribing inadequate empirical therapy, which worsens the results of patient treatment. Identification of risk factors for infection with multidrug-resistant microorganisms, careful local microbiological monitoring with detection of resistance mechanisms, implementation of antimicrobial therapy control strategy and use of rational combinations of antibacterial drugs are of great importance. In addition, the importance of using new drugs with activity against carbapenem-resistant strains, including ceftazidime/aviabactam, must be understood. This review outlines the current data on the etiology, features of diagnosis and antibacterial therapy of nosocomial pneumonia. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | Russian |
| ISSN: | 0040-3660 2309-5342 00403660 |
| Relation: | https://ter-arkhiv.ru/0040-3660/article/viewFile/623508/139227; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342 |
| DOI: | 10.26442/00403660.2023.11.202467 |
| Access URL: | https://doaj.org/article/83732a0651814787b47bceb5efb431e1 |
| Accession Number: | edsdoj.83732a0651814787b47bceb5efb431e1 |
| Database: | Directory of Open Access Journals |
| ISSN: | 00403660 23095342 |
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| DOI: | 10.26442/00403660.2023.11.202467 |
| Published in: | Терапевтический архив |
| Language: | Russian |