Academic Journal
CT pulmonary angiography findings in HIV-infected patients referred for suspected pulmonary thrombo-embolic disease
| Title: | CT pulmonary angiography findings in HIV-infected patients referred for suspected pulmonary thrombo-embolic disease |
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| Authors: | Diane Wiese, Leisha Rajkumar, Susan Lucas, David Clopton, Jacob Benfield, Jason DeBerry |
| Source: | South African Journal of Radiology, Vol 26, Iss 1, Pp e1-e6 (2022) |
| Publisher Information: | AOSIS, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| Subject Terms: | ctpa, hiv, pulmonary embolism, imaging findings, radiological, prevalence, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| More Details: | Background: South Africa bares a significant burden of HIV and imaging is commonly performed as part of the workup for respiratory distress. Objectives: The aim of this study was to document the prevalence of pulmonary thrombo-embolic disease (PTED) and other findings in HIV-infected patients referred for CT pulmonary angiography (CTPA) for suspected PTED. Method: Forty CTPA studies of documented HIV-infected individuals investigated for suspected PTED during a 1-year period were retrieved, anonymised and interpreted by three consultant radiologists. Inter-reader reliability was calculated using Free Marginal multi-rater Kappa. Results: Fourteen of the forty cases (35%) were positive for PTED. In the pulmonary embolism (PE)-positive group, 57.14% had peripheral disease and 42.86% had both peripheral and central disease. Associated findings in the PE-positive cases were pulmonary infarcts (17.5%), mosaic attenuation (17.5%) and linear atelectasis (7.5%). The most common incidental findings were solid pulmonary nodules (52.5%), non-wedge-shaped consolidation (45%), cardiomegaly (52.5%) and enlarged intra-thoracic lymph nodes (52.5%). Thirty per cent of the study population had findings related directly to the presence of PTED, whilst most cases in the study (77.5%) had pulmonary findings unrelated to PTED. In the PE-negative cases, 55% reported emergent findings that warranted immediate or urgent medical attention. Conclusion: Computed tomography pulmonary angiography imaging is critical for diagnosing PE. However, further investigation into the judicious application of CTPA in HIV-infected patients with suspected PTED is required, as CTPA findings in most of the cases in this study were unrelated to PE. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1027-202X 2078-6778 |
| Relation: | https://sajr.org.za/index.php/sajr/article/view/2273; https://doaj.org/toc/1027-202X; https://doaj.org/toc/2078-6778 |
| DOI: | 10.4102/sajr.v26i1.2273 |
| Access URL: | https://doaj.org/article/8371acd8548b480a80fd31226f8eaebd |
| Accession Number: | edsdoj.8371acd8548b480a80fd31226f8eaebd |
| Database: | Directory of Open Access Journals |
| ISSN: | 1027202X 20786778 |
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| DOI: | 10.4102/sajr.v26i1.2273 |
| Published in: | South African Journal of Radiology |
| Language: | English |