Bibliographic Details
| Title: |
Cost-Utility and Cost-effectiveness of MoodSwings 2.0, an Internet-Based Self-management Program for Bipolar Disorder: Economic Evaluation Alongside a Randomized Controlled Trial |
| Authors: |
Mary Lou Chatterton, Yong Yi Lee, Lesley Berk, Mohammadreza Mohebbi, Michael Berk, Trisha Suppes, Sue Lauder, Cathrine Mihalopoulos |
| Source: |
JMIR Mental Health, Vol 9, Iss 11, p e36496 (2022) |
| Publisher Information: |
JMIR Publications, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Psychology |
| Subject Terms: |
Psychology, BF1-990 |
| More Details: |
BackgroundInternet-delivered psychosocial interventions can overcome barriers to face-to-face psychosocial care, but limited evidence supports their cost-effectiveness for people with bipolar disorders (BDs). ObjectiveThis study aimed to conduct within-trial cost-effectiveness and cost-utility analyses of an internet-based intervention for people with BD, MoodSwings 2.0, from an Australian health sector perspective. MethodsMoodSwings 2.0 included an economic evaluation alongside an international, parallel, and individually stratified randomized controlled trial comparing an internet-based discussion forum (control; group 1), a discussion forum plus internet-based psychoeducation (group 2), and a discussion forum plus psychoeducation and cognitive behavioral tools (group 3). The trial enrolled adults (aged 21 to 65 years) with a diagnosis of BD assessed by telephone using a structured clinical interview. Health sector costs included intervention delivery and additional health care resources used by participants over the 12-month trial follow-up. Outcomes included depression symptoms measured by the Montgomery-Åsberg Depression Rating Scale (MADRS; the trial primary outcome) and quality-adjusted life years (QALYs) calculated using the short-form 6-dimension instrument derived from the 12-item version of the short-form health survey. Average incremental cost-effectiveness (cost per MADRS score) and cost-utility (cost per QALY) ratios were calculated using estimated mean differences between intervention and control groups from linear mixed effects models in the base case. ResultsIn total, 304 participants were randomized. Average health sector cost was lowest for group 2 (Aus $9431, SD Aus $8540; Aus $1=US $0.7058) compared with the control group (Aus $15,175, SD Aus $17,206) and group 3 (Aus $15,518, SD Aus $30,523), but none was statistically significantly different. The average QALYs were not significantly different among the groups (group 1: 0.627, SD 0.062; group 2: 0.618, SD 0.094; and group 3: 0.622, SD 0.087). The MADRS scores were previously shown to differ significantly between group 2 and the control group at all follow-up time points (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2368-7959 |
| Relation: |
https://mental.jmir.org/2022/11/e36496; https://doaj.org/toc/2368-7959 |
| DOI: |
10.2196/36496 |
| Access URL: |
https://doaj.org/article/835551d8e57d460890e0e91d512f7893 |
| Accession Number: |
edsdoj.835551d8e57d460890e0e91d512f7893 |
| Database: |
Directory of Open Access Journals |
