Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010.

Bibliographic Details
Title: Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010.
Authors: Lin Xiao, Dan-Li Zhang, Jill Torrie, Nathalie Auger, Nancy Gros-Louis McHugh, Zhong-Cheng Luo
Source: PLoS ONE, Vol 11, Iss 8, p e0160766 (2016)
Publisher Information: Public Library of Science (PLoS), 2016.
Publication Year: 2016
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: Cree births in Quebec are characterized by the highest reported prevalence of macrosomia (~35%) in the world. It is unclear whether Cree births are at greater elevated risk of perinatal and infant mortality than other First Nations relative to non-Aboriginal births in Quebec, and if macrosomia may be related.This was a population-based retrospective birth cohort study using the linked birth-infant death database for singleton births to mothers from Cree (n = 5,340), other First Nations (n = 10,810) and non-Aboriginal (n = 229,960) communities in Quebec, 1996-2010. Community type was ascertained by residential postal code and municipality name. The primary outcomes were perinatal and infant mortality.Macrosomia (birth weight for gestational age >90th percentile) was substantially more frequent in Cree (38.0%) and other First Nations (21.9%) vs non-Aboriginal (9.4%) communities. Comparing Cree and other First Nations vs non-Aboriginal communities, perinatal mortality rates were 1.52 (95% confidence intervals 1.17, 1.98) and 1.34 (1.10, 1.64) times higher, and infant mortality rates 2.27 (1.71, 3.02) and 1.49 (1.16, 1.91) times higher, respectively. The risk elevations in perinatal and infant death in Cree communities attenuated after adjusting for maternal characteristics (age, education, marital status, parity), but became greater after further adjustment for birth weight (small, appropriate, or large for gestational age).Cree communities had greater risk elevations in perinatal and infant mortality than other First Nations relative to non-Aboriginal communities in Quebec. High prevalence of macrosomia did not explain the elevated risk of perinatal and infant mortality in Cree communities.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1932-6203
Relation: http://europepmc.org/articles/PMC4982632?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0160766
Access URL: https://doaj.org/article/8350f7c070494ac39dddec21f601a31c
Accession Number: edsdoj.8350f7c070494ac39dddec21f601a31c
Database: Directory of Open Access Journals
More Details
ISSN:19326203
DOI:10.1371/journal.pone.0160766
Published in:PLoS ONE
Language:English