Bibliographic Details
| Title: |
Structure-based design of chimeric antigens for multivalent protein vaccines |
| Authors: |
S. Hollingshead, I. Jongerius, R. M. Exley, S. Johnson, S. M. Lea, C. M. Tang |
| Source: |
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
| Publisher Information: |
Nature Portfolio, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Factor H binding protein (fHbp) and PorA are components of experimental serogroup B N. meningitidis vaccines. Here the authors graft the VR2 loop of PorA onto an fHBp-based scaffold to demonstrate proof-of-principle of a chimeric antigen strategy and vaccination against meningococcal disease. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-018-03146-7 |
| Access URL: |
https://doaj.org/article/823538b9d7624657ba20526bd2a41c1a |
| Accession Number: |
edsdoj.823538b9d7624657ba20526bd2a41c1a |
| Database: |
Directory of Open Access Journals |
