P5.15 EVALUATION OF AORTIC 18F-NAF TRACER UPTAKE DETECTED USING PET/CT IN PREDICTING AORTIC CALCIFICATION OVER A 4-YEAR FOLLOW-UP PERIOD

Bibliographic Details
Title:	P5.15 EVALUATION OF AORTIC 18F-NAF TRACER UPTAKE DETECTED USING PET/CT IN PREDICTING AORTIC CALCIFICATION OVER A 4-YEAR FOLLOW-UP PERIOD
Authors:	Marina Cecelja, Amelia Moore, Ignac Fogelman, Michelle Frost, Phillip Chowienczyk
Source:	Artery Research, Vol 12 (2015)
Publisher Information:	BMC, 2015.
Publication Year:	2015
Collection:	LCC:Specialties of internal medicine LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms:	Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details:	Background: Uptake of 18F-sodium fluoride (18F-NaF) in the aortic wall may reflect metabolically active areas of calcification, an important predictor of cardiovascular morbidity and mortality when detected by computed tomography (CT). The aim of this project was to determine if 18F-NaF uptake in the aorta can predict development of calcification as detected by CT. Method and results: Twenty one postmenopausal women (mean age 62±6 years, range 52-74), underwent assessment of aortic 18F-NaF uptake using positron emission tomography/computer tomography (PET/CT) at baseline and after a mean follow-up of 3.7±1.3 years. Tracer uptake was quantified by calculating the target-to-background ratios (TBR). At baseline, there was a trend to a positive correlation between CT calcium volume score and tracer uptake (r=0.33, P=0.15). Over the follow-up period aortic CT calcium volume increased from 0.45±0.62 to 0.71±0.93 cm3 (P
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	1876-4401
Relation:	https://www.atlantis-press.com/article/125930627/view; https://doaj.org/toc/1876-4401
DOI:	10.1016/j.artres.2015.10.279
Access URL:	https://doaj.org/article/812c7c91eea640ce8f3843f952cf7f7b
Accession Number:	edsdoj.812c7c91eea640ce8f3843f952cf7f7b
Database:	Directory of Open Access Journals

More Details
ISSN:	18764401
DOI:	10.1016/j.artres.2015.10.279
Published in:	Artery Research
Language:	English