Academic Journal
A Pilot Study of Transbronchial Biopsy Using Endobronchial Ultrasonography with a Guide Sheath in the Diagnosis of Peripheral Pulmonary Lesions in Patients with Interstitial Lung Disease
| Title: | A Pilot Study of Transbronchial Biopsy Using Endobronchial Ultrasonography with a Guide Sheath in the Diagnosis of Peripheral Pulmonary Lesions in Patients with Interstitial Lung Disease |
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| Authors: | Takayasu Ito, Tomoki Kimura, Kensuke Kataoka, Shotaro Okachi, Keiko Wakahara, Naozumi Hashimoto, Yasuhiro Kondoh |
| Source: | Diagnostics, Vol 11, Iss 12, p 2269 (2021) |
| Publisher Information: | MDPI AG, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medicine (General) |
| Subject Terms: | bronchoscopy, endosonograph, image-guided biopsy, interstitial lung diseases, lung neoplasms, Medicine (General), R5-920 |
| More Details: | The occurrence of interstitial lung disease (ILD) with peripheral pulmonary lesions (PPLs) is closely linked to the development of lung cancer. Yet, the best diagnostic approach for identifying PPLs in patients with ILD remains elusive. This study retrospectively investigated the application of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS) to the effective and safe diagnosis of PPLs when compared with conventional TBB. The study sample included a consecutive series of 19 patients with ILD who underwent conventional TBB or TBB using EBUS-GS at Tosei General Hospital between 1 April 2013 and 31 October 2015. The two techniques were compared based on diagnostic yield and associated complications. The diagnostic yield of EBUS-GS TBB was significantly higher than that of conventional TBB (p = 0.009), especially for small lesions (≤20 mm), lesions located in the lower lobes, lesions with a positive bronchus sign, and lesions visible by chest radiography (p = 0.010, p = 0.022, p = 0.006, and p = 0.002, respectively). There were no significant differences in complication rates. Therefore, EBUS-GS is an effective alternative for the diagnosis of PPLs in patients with ILD, without additional complications. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 11122269 2075-4418 |
| Relation: | https://www.mdpi.com/2075-4418/11/12/2269; https://doaj.org/toc/2075-4418 |
| DOI: | 10.3390/diagnostics11122269 |
| Access URL: | https://doaj.org/article/d812150fb50641ab8c97861f65fc7ce8 |
| Accession Number: | edsdoj.812150fb50641ab8c97861f65fc7ce8 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 11122269 20754418 |
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| DOI: | 10.3390/diagnostics11122269 |
| Published in: | Diagnostics |
| Language: | English |