Bibliographic Details
| Title: |
Pressure-controlled ventilation-volume guaranteed mode improves bronchial mucus transport velocity in patients during laparoscopic surgery for gynecological oncology: a randomized controlled study |
| Authors: |
Chao Deng, Tao Xu, Xue-kai Wang, Deng-feng Gu |
| Source: |
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-9 (2023) |
| Publisher Information: |
BMC, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Anesthesiology |
| Subject Terms: |
Airway mucosa, Pressure-controlled ventilation-volume guaranteed, Volume-controlled ventilation, Bronchial mucus transport velocity, Laparoscopic surgery, Gynecological oncology, Anesthesiology, RD78.3-87.3 |
| More Details: |
Abstract Background Mechanical ventilation during general anesthesia may impair airway mucosal function. This study aimed to investigate the effect of pressure-controlled ventilation-volume guaranteed (PCV-VG) on bronchial mucus transport velocity (BTV) in patients during laparoscopic surgery for gynecological oncology compared with volume controlled ventilation (VCV). Methods 66 patients undergoing elective a laparoscopic surgery for gynecological oncology. The patients were randomized into two group receiving either PCV-VG or VCV. a drop of methylene blue was placed on the surface of the airway mucosa under the bronchoscopeand, then the distance the dye movement was measured after 2, 4, and 6 min. Outcomes were assessed at T0 (5 min after endotracheal intubation and before initiation of pneumoperitoneum), T1 and T2 (1 and 2 h after stabilization of pneumoperitoneum respectively). BTV at T0, T1 and T2 was the primary outcome. Secondary outcomes included heart rate (HR), mean arterial pressure (MAP), body temperature, end-tidal CO2 pressure (PETCO2), tidal volume(VT), peak inspiratory pressure (PIP), mean inspiratory pressure (Pmean), respiratory rate (RR), and dynamic compliance (CDyn) at T0, T1, and T2. Results 64 patients were included in the analysis. The median [interquartile range] BTV was significantly lower in VCV group at T1 and T2 that at T0 (P 0.05). Compared with the PCV-VG group, BTV in VCV group significantly decreased at T2 (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2253 |
| Relation: |
https://doaj.org/toc/1471-2253 |
| DOI: |
10.1186/s12871-023-02343-2 |
| Access URL: |
https://doaj.org/article/c811fcc093fd4afdbf41211eed42e1d3 |
| Accession Number: |
edsdoj.811fcc093fd4afdbf41211eed42e1d3 |
| Database: |
Directory of Open Access Journals |
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