Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis

Bibliographic Details
Title: Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis
Authors: Hidehiro Hayashi, Shin Miura, Fumiyoshi Fujishima, Shimpei Kuniyoshi, Kiyoshi Kume, Kazuhiro Kikuta, Shin Hamada, Tetsuya Takikawa, Ryotaro Matsumoto, Mio Ikeda, Takanori Sano, Fumiya Kataoka, Akira Sasaki, Misako Sakano, Atsushi Masamune
Source: Diagnostics, Vol 12, Iss 10, p 2464 (2022)
Publisher Information: MDPI AG, 2022.
Publication Year: 2022
Collection: LCC:Medicine (General)
Subject Terms: granulocytic epithelial lesions, main pancreatic duct narrowing, inflammatory bowel disease, ulcerative colitis, International Consensus Diagnostic Criteria, Medicine (General), R5-920
More Details: In Japan, type 1 autoimmune pancreatitis (AIP) is the most common type of AIP; type 2 AIP is rare. The aim of this study was to clarify the usefulness of endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNAB) for the diagnosis of type 2 AIP. We analyzed the tissue specimens of 10 patients with suspected type 2 AIP who underwent EUS-FNAB at our hospital between April 2009 and March 2021 for tissue volume and histopathological diagnostic performance. The male-to-female ratio of the patients was 8:2, and the patient age (mean ± standard deviation) was 35.6 ± 15.5 years. EUS-FNAB provided sufficient tissue volume, with high-power field >10 in eight patients (80.0%). Based on the International Consensus Diagnostic Criteria (ICDC), four patients (40.0%) had histological findings corresponding to ICDC level 1, and five patients (50.0%) had histological findings corresponding to ICDC level 2. The results of this study show that EUS-FNB can be considered an alternative method to resection and core-needle biopsy for the collection of tissue samples of type 2 AIP.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2075-4418
Relation: https://www.mdpi.com/2075-4418/12/10/2464; https://doaj.org/toc/2075-4418
DOI: 10.3390/diagnostics12102464
Access URL: https://doaj.org/article/811f8f2314454fea94fd7e8e92dc137a
Accession Number: edsdoj.811f8f2314454fea94fd7e8e92dc137a
Database: Directory of Open Access Journals
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More Details
ISSN:20754418
DOI:10.3390/diagnostics12102464
Published in:Diagnostics
Language:English