Do We Need to Act Fast in Central Serous Chorioretinopathy? - A Comparative Study
| Title: | Do We Need to Act Fast in Central Serous Chorioretinopathy? - A Comparative Study |
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| Authors: | Jayati Pandey, Anchal Tripathi, Lav Pathak, Perwez Khan, Lubna Khan |
| Source: | Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 18, Iss 1, Pp 52-57 (2025) |
| Publisher Information: | Wolters Kluwer Medknow Publications, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Medicine |
| Subject Terms: | acetazolamide, central serous chorioretinopathy, double frequency nd-yag laser, eplerenone, Medicine |
| More Details: | Background: Central serous chorioretinopathy (CSCR) is a sporadic disorder of the outer blood-retinal barrier, characterized by a localized detachment of the sensory retina usually affecting one eye in young males. Usually, a self-limiting disease various treatments have been investigated in recent times. Aim: To evaluate the final visual outcome, recurrence rate, and possible complications in patients of CSCR treated with observation, oral acetazolamide, oral eplerenone, and double-frequency neodynium-doped yttrium aluminium garnet (ND-YAG) laser photocoagulation. Methods: A prospective interventional study was conducted on patients newly diagnosed with CSCR. The patients were divided into four groups namely: Group A on observation, Group B on oral acetazolamide Group C on oral eplerenone, and Group D on Double frequency Nd-YAG laser. The visual recovery, recurrence rate, and possible complications of these therapies were compared. Results: The study comprised of 76 patients. Group D patients showed the fastest improvement in visual acuity at 2 weeks. At 12 weeks, all groups had comparable improvement. Three patients in Group A, 1 each in Groups B and D, and 2 in Group C showed recurrence. Paresthesia, numbness, and gastric upset related to acetazolamide were noted in 5 patients of Group B. However, 16.7% of cases in Group A, 10.5% in Group B, 5.3% in Group C, and 5% in Group D showed leakage on Fundus fluorescent angiography after 12 weeks. Conclusion: In acute CSCR eplerenone seems to be efficient with the least side effects and early resolution. In chronic cases, Double frequency Nd-YAG laser seems to give better results. Early treatment should be given for better visual recovery of patients. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2589-8302 2589-8310 |
| Relation: | https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_38_24; https://doaj.org/toc/2589-8302; https://doaj.org/toc/2589-8310 |
| DOI: | 10.4103/mjdrdypu.mjdrdypu_38_24 |
| Access URL: | https://doaj.org/article/c80a41c96b334ceea545a31fe73c045c |
| Accession Number: | edsdoj.80a41c96b334ceea545a31fe73c045c |
| Database: | Directory of Open Access Journals |
| ISSN: | 25898302 25898310 |
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| DOI: | 10.4103/mjdrdypu.mjdrdypu_38_24 |
| Published in: | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
| Language: | English |