Risk factors for early local lymph node recurrence of thoracic ESCC after McKeown esophagectomy

Bibliographic Details
Title: Risk factors for early local lymph node recurrence of thoracic ESCC after McKeown esophagectomy
Authors: Liang Dai, Yong-Bo Yang, Ya-Ya Wu, Hao Fu, Wan-Pu Yan, Yao Lin, Zi-Ming Wang, Ke-Neng Chen
Source: Frontiers in Surgery, Vol 9 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Surgery
Subject Terms: early local lymph node recurrence, mckeown esophagectomy, risk factors, esophageal squamous cell carcinoma, prognosis of esophageal cancer, Surgery, RD1-811
More Details: ObjectivesEven underwent radical resection, some patients of thoracic esophageal squamous cell carcinoma (ESCC) are still exposed to local recurrence in a short time. To this end, the present study sought to differentiate patient subgroups by assessing risk factors for postoperative early (within one year) local lymph node recurrence (PELLNR).MethodsESCC patients were selected from a prospective database, and divided into high- and low-risk groups according to the time of their local lymphatic recurrence (within one year or later). Survival analysis was conducted by the Cox regression model to evaluate the overall survival (OS) between the two groups. The hazard ratio (HR) and 95% confidence interval (CI) of different variables were also calculated. Logistic regression analysis was used to explore the high-risk factors for PELLNR with the odds ratio (OR) and 95% CI calculated.ResultsA total of 432 cases were included. The survival of patients in the high-risk group (n = 47) was significantly inferior to the low-risk group (n = 385) (HR = 11.331, 95% CI: 6.870–16.688, P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2296-875X
Relation: https://www.frontiersin.org/articles/10.3389/fsurg.2022.1043755/full; https://doaj.org/toc/2296-875X
DOI: 10.3389/fsurg.2022.1043755
Access URL: https://doaj.org/article/8062395e0c924a50952ee582a37e5c3b
Accession Number: edsdoj.8062395e0c924a50952ee582a37e5c3b
Database: Directory of Open Access Journals
More Details
ISSN:2296875X
DOI:10.3389/fsurg.2022.1043755
Published in:Frontiers in Surgery
Language:English