Clinical implications of coronavirus disease 2019 in neonates
| Title: | Clinical implications of coronavirus disease 2019 in neonates |
|---|---|
| Authors: | Do-Hyun Kim |
| Source: | Clinical and Experimental Pediatrics, Vol 64, Iss 4, Pp 157-164 (2021) |
| Publisher Information: | The Korean Pediatric Society, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Pediatrics |
| Subject Terms: | covid-19, coronavirus, neonate, sars-cov-2, Pediatrics, RJ1-570 |
| More Details: | Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, a small number of coronavirus disease 2019 (COVID-19) cases in neonates have been reported worldwide. Neonates currently account for only a minor proportion of the pediatric population affected by COVID-19. Thus, data on the epidemiological and clinical features of COVID-19 in neonates are limited. Approximately 3% of neonates born to mothers with COVID-19 reportedly tested positive for SARS-CoV-2. Current limited data on neonates with COVID-19 suggest that neonatal COVID-19 shows a relatively benign course despite a high requirement for mechanical ventilation. However, neonates with pre-existing medical conditions and preterm infants appear to be at a higher risk of developing severe COVID-19. The greatest perinatal concern of the COVID-19 pandemic is the possibility of vertical transmission, especially transplacental transmission of SARS-CoV-2. Although direct evidence of the vertical transmission of SARS-CoV-2 is lacking, its possibility during late pregnancy cannot be ruled out. This review summarizes available case studies on COVID-19 in neonates and introduces what is currently known about neonatal COVID-19 with focus on its vertical transmission. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2713-4148 42908965 |
| Relation: | http://www.e-cep.org/upload/pdf/cep-2020-01795.pdf; https://doaj.org/toc/2713-4148 |
| DOI: | 10.3345/cep.2020.01795 |
| Access URL: | https://doaj.org/article/c8051083b73e42908965a9ee98d4dcb0 |
| Accession Number: | edsdoj.8051083b73e42908965a9ee98d4dcb0 |
| Database: | Directory of Open Access Journals |
| ISSN: | 27134148 42908965 |
|---|---|
| DOI: | 10.3345/cep.2020.01795 |
| Published in: | Clinical and Experimental Pediatrics |
| Language: | English |