Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia

Bibliographic Details
Title: Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia
Authors: Dimitrios Papaioannou, Hatice G. Ozer, Deedra Nicolet, Amog P. Urs, Tobias Herold, Krzysztof Mrózek, Aarif M.N. Batcha, Klaus H. Metzeler, Ayse S. Yilmaz, Stefano Volinia, Marius Bill, Jessica Kohlschmidt, Maciej Pietrzak, Christopher J. Walker, Andrew J. Carroll, Jan Braess, Bayard L. Powell, Ann-Kathrin Eisfeld, Geoffrey L. Uy, Eunice S. Wang, Jonathan E. Kolitz, Richard M. Stone, Wolfgang Hiddemann, John C. Byrd, Clara D. Bloomfield, Ramiro Garzon
Source: Haematologica, Vol 107, Iss 5 (2021)
Publisher Information: Ferrata Storti Foundation, 2021.
Publication Year: 2021
Collection: LCC:Diseases of the blood and blood-forming organs
Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5
More Details: Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the nucleotide sequences of lncRNA in AML patients is unknown. Herein, we analyzed total RNA sequencing data of 377 younger adults (aged
Document Type: article
File Description: electronic resource
Language: English
ISSN: 0390-6078
1592-8721
Relation: https://haematologica.org/article/view/10331; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721
DOI: 10.3324/haematol.2021.266643
Access URL: https://doaj.org/article/7f9bf447eead48ccb2195be68f8f7b08
Accession Number: edsdoj.7f9bf447eead48ccb2195be68f8f7b08
Database: Directory of Open Access Journals
More Details
ISSN:03906078
15928721
DOI:10.3324/haematol.2021.266643
Published in:Haematologica
Language:English