Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia
Title: | Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia |
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Authors: | Dimitrios Papaioannou, Hatice G. Ozer, Deedra Nicolet, Amog P. Urs, Tobias Herold, Krzysztof Mrózek, Aarif M.N. Batcha, Klaus H. Metzeler, Ayse S. Yilmaz, Stefano Volinia, Marius Bill, Jessica Kohlschmidt, Maciej Pietrzak, Christopher J. Walker, Andrew J. Carroll, Jan Braess, Bayard L. Powell, Ann-Kathrin Eisfeld, Geoffrey L. Uy, Eunice S. Wang, Jonathan E. Kolitz, Richard M. Stone, Wolfgang Hiddemann, John C. Byrd, Clara D. Bloomfield, Ramiro Garzon |
Source: | Haematologica, Vol 107, Iss 5 (2021) |
Publisher Information: | Ferrata Storti Foundation, 2021. |
Publication Year: | 2021 |
Collection: | LCC:Diseases of the blood and blood-forming organs |
Subject Terms: | Diseases of the blood and blood-forming organs, RC633-647.5 |
More Details: | Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the nucleotide sequences of lncRNA in AML patients is unknown. Herein, we analyzed total RNA sequencing data of 377 younger adults (aged |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 0390-6078 1592-8721 |
Relation: | https://haematologica.org/article/view/10331; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721 |
DOI: | 10.3324/haematol.2021.266643 |
Access URL: | https://doaj.org/article/7f9bf447eead48ccb2195be68f8f7b08 |
Accession Number: | edsdoj.7f9bf447eead48ccb2195be68f8f7b08 |
Database: | Directory of Open Access Journals |
ISSN: | 03906078 15928721 |
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DOI: | 10.3324/haematol.2021.266643 |
Published in: | Haematologica |
Language: | English |