Limbic encephalitis with relapsing polychondritis: persistent white matter lesions and brain atrophy

Bibliographic Details
Title:	Limbic encephalitis with relapsing polychondritis: persistent white matter lesions and brain atrophy
Authors:	Zilong Zhu, Decai Tian, Ning Ren, Zhihong Zhao, Xin Wang, Lei Chen
Source:	Journal of International Medical Research, Vol 46 (2018)
Publisher Information:	SAGE Publishing, 2018.
Publication Year:	2018
Collection:	LCC:Medicine (General)
Subject Terms:	Medicine (General), R5-920
More Details:	Relapsing polychondritis (RP) is a rare autoimmune disorder affecting cartilage. Limbic encephalitis is a rare central nervous system manifestation of RP. This current case report describes a 66-year-old Chinese male patient who complained of developing myoclonus in the left leg, ataxia and speech difficulties 3 weeks prior to hospital admission. The patient presented with cognitive impairment, sleep disorder and extrapyramidal symptoms. The patient was diagnosed with RP that affected auricular cartilage, which also manifested as limbic encephalitis. Magnetic resonance imaging showed bilateral temporal lobe lesions involving the hippocampi and basal ganglia. Signal abnormalities in the white matter persisted during the 15-month follow-up period after treatment with corticosteroids and intravenous immunoglobulin. Over the same period, the bilateral hippocampi showed significant atrophy.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	0300-0605 1473-2300 03000605
Relation:	https://doaj.org/toc/0300-0605; https://doaj.org/toc/1473-2300
DOI:	10.1177/0300060518805593
Access URL:	https://doaj.org/article/7f97e0b5633343488fea04dea8ee4805
Accession Number:	edsdoj.7f97e0b5633343488fea04dea8ee4805
Database:	Directory of Open Access Journals

More Details
ISSN:	03000605 14732300
DOI:	10.1177/0300060518805593
Published in:	Journal of International Medical Research
Language:	English