Single-cell multiomics sequencing reveals the functional regulatory landscape of early embryos

Bibliographic Details
Title: Single-cell multiomics sequencing reveals the functional regulatory landscape of early embryos
Authors: Yang Wang, Peng Yuan, Zhiqiang Yan, Ming Yang, Ying Huo, Yanli Nie, Xiaohui Zhu, Jie Qiao, Liying Yan
Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Publisher Information: Nature Portfolio, 2021.
Publication Year: 2021
Collection: LCC:Science
Subject Terms: Science
More Details: Extensive epigenetic reprogramming occurs during preimplantation embryo development. Here the authors develop a single cell multiomics sequencing technology that enables profiling of genome-wide chromatin accessibility, DNA methylation and RNA expression in the same individual cell and apply this method to study mouse preimplantation embryos.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-021-21409-8
Access URL: https://doaj.org/article/7efdae7a7382401c91ad28ab2db63e3d
Accession Number: edsdoj.7efdae7a7382401c91ad28ab2db63e3d
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-021-21409-8
Published in:Nature Communications
Language:English