Bibliographic Details
| Title: |
Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals |
| Authors: |
R. Brandon Stacey, Trinity Vera, Timothy M. Morgan, Jennifer H. Jordan, Matthew C. Whitlock, Michael E. Hall, Sujethra Vasu, Craig Hamilton, Dalane W. Kitzman, W. Gregory Hundley |
| Source: |
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-11 (2018) |
| Publisher Information: |
Elsevier, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Stress testing, Cardiovascular events, Aging, Sex difference, Cardiovascular magnetic resonance, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background Current guidelines for assessing the risk of experiencing a hospitalized cardiovascular (CV) event discourage stress testing of asymptomatic individuals; however, these recommendations are based on evidence gathered primarily from those aged 55 years without CV-related symptoms nor known coronary artery disease, but otherwise at increased risk for a future CV event due to pre-existing hypertension or diabetes mellitus for at least 5 years. After adjusting for the demographics and CV risk factors, log-rank test and Cox proportional hazards models determined the additional predictive value of the stress test results for forecasting hospitalized CV events/survival. Either stress-induced LV wall motion abnormalities or perfusion defects were used to indicate myocardial ischemia. Results Participants averaged 68 ± 8 years in age; 39% men, 75% Caucasian. There were 38 hospitalized CV events or deaths which occurred during a mean follow-up of 58 months. Using Kaplan-Meier analyses, myocardial ischemia identified future CV events/survival (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1532-429X |
| Relation: |
http://link.springer.com/article/10.1186/s12968-018-0492-5; https://doaj.org/toc/1532-429X |
| DOI: |
10.1186/s12968-018-0492-5 |
| Access URL: |
https://doaj.org/article/7ecac04866bc419eb4305ac92f96c099 |
| Accession Number: |
edsdoj.7ecac04866bc419eb4305ac92f96c099 |
| Database: |
Directory of Open Access Journals |
