Do people with diabetes have a higher risk of developing postoperative endophthalmitis after cataract surgery? A systematic review and meta-analysis

Bibliographic Details
Title: Do people with diabetes have a higher risk of developing postoperative endophthalmitis after cataract surgery? A systematic review and meta-analysis
Authors: Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan
Source: Journal of Ophthalmic Inflammation and Infection, Vol 15, Iss 1, Pp 1-16 (2025)
Publisher Information: SpringerOpen, 2025.
Publication Year: 2025
Collection: LCC:Ophthalmology
Subject Terms: Postoperative endophthalmitis, Diabetes mellitus, Cataract surgery, Posterior capsule rupture, Antibiotic prophylactic, Meta-analysis, Ophthalmology, RE1-994
More Details: Abstract Purpose Postoperative endophthalmitis (POE) is a rare but severe complication of cataract surgery. While diabetes mellitus may increase the risk of POE, the relationship remains unclear. Methods A systematic review and meta-analysis were conducted following PRISMA guidelines. PubMed, Scopus, Medline, Embase, and Google Scholar were searched for relevant studies up to September 10, 2024. The study included both randomized controlled trials and observational studies that evaluated POE outcomes in cataract surgery patients, comparing people with and without diabetes. Random-effects models were used to calculate pooled odds ratios (OR) with 95% confidence intervals (CI). Results Nine studies were included in the systematic review, with seven analyzed in the meta-analysis. The review on POE in people with diabetes undergoing cataract surgery revealed a higher incidence in this group, with a pooled odds ratio (OR) of 1.174 (95% CI: 1.109 to 1.242; p = 0.000) and an incidence rate of 0.261%, compared to 0.242% in people without diabetes. Males with diabetes had a 1.634 times higher risk of POE (p = 0.048), while diabetes and hypertension together increased risk by 3.961 times (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1869-5760
Relation: https://doaj.org/toc/1869-5760
DOI: 10.1186/s12348-025-00483-9
Access URL: https://doaj.org/article/c7da892df64b499c902f26e6f69c7d14
Accession Number: edsdoj.7da892df64b499c902f26e6f69c7d14
Database: Directory of Open Access Journals
More Details
ISSN:18695760
DOI:10.1186/s12348-025-00483-9
Published in:Journal of Ophthalmic Inflammation and Infection
Language:English