Title: |
Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model |
Authors: |
Song Liya, Li Lihua |
Source: |
Open Life Sciences, Vol 19, Iss 1, Pp 3898-918 (2024) |
Publisher Information: |
De Gruyter, 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Biology (General) |
Subject Terms: |
obesity rat model, high-fat diet, phosphatidylinositol-3-kinase/protein kinase b, toll-like receptor/nuclear factor kappa b, differences, expression, Biology (General), QH301-705.5 |
More Details: |
This study investigated the effects of activation and inhibition of the PI3K/AKT and TLR-4/NF-κB signaling pathways on insulin resistance in a high-fat diet-induced obese rat model. The results indicate that a high-fat diet can activate these signaling pathways by regulating the expression of related proteins, affecting metabolic health. Rat PI3K/AKT pathway protein. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2391-5412 |
Relation: |
https://doaj.org/toc/2391-5412 |
DOI: |
10.1515/biol-2022-1014 |
Access URL: |
https://doaj.org/article/7d247e0acfe7428694e97dc949ffff35 |
Accession Number: |
edsdoj.7d247e0acfe7428694e97dc949ffff35 |
Database: |
Directory of Open Access Journals |