Bibliographic Details
Title: |
Causes of death in women with breast cancer: a risks and rates study on a population-based cohort |
Authors: |
Paolo Contiero, Roberto Boffi, Alessandro Borgini, Sabrina Fabiano, Andrea Tittarelli, Michael Mian, Fabio Vittadello, Susi Epifani, Antonino Ardizzone, Claudia Cirilli, Lorenza Boschetti, Stefano Marguati, Giuseppe Cascone, Rosario Tumino, Anna Clara Fanetti, Paola Giumelli, Giuseppa Candela, Tiziana Scuderi, Maurizio Castelli, Salvatore Bongiorno, Giulio Barigelletti, Viviana Perotti, Chiara Veronese, Fabio Turazza, Marina Crivaro, Giovanna Tagliabue, the MAPACA Working Group |
Source: |
Frontiers in Oncology, Vol 13 (2023) |
Publisher Information: |
Frontiers Media S.A., 2023. |
Publication Year: |
2023 |
Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
Subject Terms: |
cardio-oncology, geographic variation, breast cancer, cardiovascular disease, respiratory disease, cause-specific death, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
More Details: |
IntroductionThe increasing survival of patients with breast cancer has prompted the assessment of mortality due to all causes of death in these patients. We estimated the absolute risks of death from different causes, useful for health-care planning and clinical prediction, as well as cause-specific hazards, useful for hypothesis generation on etiology and risk factors.Materials and methodsUsing data from population-based cancer registries we performed a retrospective study on a cohort of women diagnosed with primary breast cancer. We carried out a competing-cause analysis computing cumulative incidence functions (CIFs) and cause-specific hazards (CSHs) in the whole cohort, separately by age, stage and registry area.ResultsThe study cohort comprised 12,742 women followed up for six years. Breast cancer showed the highest CIF, 13.71%, and cardiovascular disease was the second leading cause of death with a CIF of 3.60%. The contribution of breast cancer deaths to the CIF for all causes varied widely by age class: 89.25% in women diagnosed at age |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2234-943X |
Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2023.1270877/full; https://doaj.org/toc/2234-943X |
DOI: |
10.3389/fonc.2023.1270877 |
Access URL: |
https://doaj.org/article/d7af23b698564967a054b96a0df7ea09 |
Accession Number: |
edsdoj.7af23b698564967a054b96a0df7ea09 |
Database: |
Directory of Open Access Journals |