Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in recovery phase: a randomized, double-blind, crossover study

Bibliographic Details
Title: Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in recovery phase: a randomized, double-blind, crossover study
Authors: Maiane da Silva Feitoza, Jaqueline Ribas de Melo, Wladimir Musetti Medeiros, Gabriel Grizzo Cucato, Rafael Stelmach, Alberto Cukier, Celso Ricardo Fernandes de Carvalho, Felipe Augusto Rodrigues Mendes
Source: Motriz: Revista de Educacao Fisica, Vol 23, Iss 3 (2017)
Publisher Information: Universidade Estadual Paulista (UNESP), 2017.
Publication Year: 2017
Collection: LCC:Sports
LCC:Sports medicine
Subject Terms: salbutamol, exercise, eeart rate, blood pressure, healthy subject, Sports, GV557-1198.995, Sports medicine, RC1200-1245
More Details: ABSTRACT Aim To evaluate the effect of the short-acting beta agonists (SABAs) salbutamol on cardiovascular response rest, exercise and recovery phase. Methods This study was conducted as a randomized, double-blind, placebo controlled, crossover study in 15 healthy adults, with a mean age of 30.2±6.6 years. Participants underwent a maximal effort test on two non-consecutive days with 400 mcg of salbutamol or placebo. Throughout the protocol, the variables HR, blood pressure (BP), perceived rate of effort (modified Borg scale) and peak expiratory flow (PEF) were monitored. Results After salbutamol, baseline HR and PEF had increase from 71±8 to 80±11 bpm (p0.05). Conclusion Administration of salbutamol increased rest heart rate; however, did not change heart rate, blood pressure and perceived exertion during exercise or recovery. This suggests that the salbutamol administration is safe and does not affect exercise intensity prescription in healthy subjects.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1980-6574
Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742017000300308&lng=en&tlng=en; https://doaj.org/toc/1980-6574
DOI: 10.1590/s1980-6574201700030012
Access URL: https://doaj.org/article/7aacefe3e5f24959bcf1eb2d5dba0156
Accession Number: edsdoj.7aacefe3e5f24959bcf1eb2d5dba0156
Database: Directory of Open Access Journals
More Details
ISSN:19806574
DOI:10.1590/s1980-6574201700030012
Published in:Motriz: Revista de Educacao Fisica
Language:English