Bibliographic Details
| Title: |
Clinicopathological features, treatment patterns, and prognosis of squamous cell carcinoma of the breast: an NCDB analysis |
| Authors: |
Liling Zhu, Kai Chen |
| Source: |
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019) |
| Publisher Information: |
BMC, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
Breast cancer, Squamous cell carcinoma, Infiltrating ductal carcinoma, Survival, Endocrine therapy, Chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Abstract Background Squamous cell carcinoma (SCC) of the breast is a rare malignancy. The clinicopathological features, treatment patterns and prognosis of SCC of the breast is still unclear. Methods In this study, we performed a 1:4 SCC-IDC (infiltrating ductal carcinoma) matching analysis of patients diagnosed between 2004 and 2014, using the data from the national cancer database. We used Chi-square test to compare the clinicopathological features and treatment patterns between SCC (n = 686) and IDC (n = 2744) patients. We used Kaplan-Meier analysis and Cox-regression to estimate the survival of SCC and IDC patients. Results We observed that SCC patients are more likely to have T3–4, grade III, and ER negative diseases, when compared to IDC patients. Breast conserving surgery (BCS) (58.3% vs 65.4%, p = 0.048), as well as radiotherapy after BCS (65.3% vs. 83.0%, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2407 |
| Relation: |
http://link.springer.com/article/10.1186/s12885-018-5212-x; https://doaj.org/toc/1471-2407 |
| DOI: |
10.1186/s12885-018-5212-x |
| Access URL: |
https://doaj.org/article/7aa5eec84a7a40bc89bc5d5725c1e83a |
| Accession Number: |
edsdoj.7aa5eec84a7a40bc89bc5d5725c1e83a |
| Database: |
Directory of Open Access Journals |
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