A Unique Constellation of Multiple Cranial Neuropathies in a Patient with Preeclampsia

Bibliographic Details
Title: A Unique Constellation of Multiple Cranial Neuropathies in a Patient with Preeclampsia
Authors: Pardis Zarifkar, Klaus Hansen, Clarissa Crone, Kirsten Svenstrup, Vibeke Andrée Larsen, William Kristian Karlsson
Source: Case Reports in Neurology, Vol 14, Iss 2, Pp 256-260 (2022)
Publisher Information: Karger Publishers, 2022.
Publication Year: 2022
Collection: LCC:Neurology. Diseases of the nervous system
Subject Terms: cranial neuropathy, hypertension, hypoglossal nerve, multiple cranial neuropathies, preeclampsia, pregnancy, Neurology. Diseases of the nervous system, RC346-429
More Details: A 36-year-old nullipara at 35 weeks of gestation woke up with slurred speech and dysphagia. The next day, she developed abruption of the placenta, underwent an acute cesarean, and was diagnosed with severe preeclampsia. Neurologic examination revealed flaccid dysarthria, bilateral soft palate palsy, reduced taste of the left posterior tongue, left-sided tongue deviation, and paralysis of the left sternocleidomastoid and trapezius muscles. MRI revealed left-sided tongue edema compatible with acute left hypoglossal nerve denervation and electromyography of the left trapezius and glossal muscles showed profuse denervation potentials. In conclusion, multiple cranial neuropathies may occur in and even be a presenting symptom of preeclampsia. In this study, we report the first case of multiple cranial neuropathies involving cranial nerves IX, X, XI, and XII in a patient with preeclampsia. Possible pathogenic mechanisms of cranial neuropathy in preeclampsia include immune-mediated neuropathy with or without demyelination, microvascular thromboses, and perineural edema.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1662-680X
Relation: https://www.karger.com/Article/FullText/524459; https://doaj.org/toc/1662-680X
DOI: 10.1159/000524459
Access URL: https://doaj.org/article/79a00b05add6493abc10a0c21c7beb64
Accession Number: edsdoj.79a00b05add6493abc10a0c21c7beb64
Database: Directory of Open Access Journals
More Details
ISSN:1662680X
DOI:10.1159/000524459
Published in:Case Reports in Neurology
Language:English