Bibliographic Details
| Title: |
Chronic Inflammation-Related HPV: A Driving Force Speeds Oropharyngeal Carcinogenesis. |
| Authors: |
Xin Liu, Xiangrui Ma, Zhengge Lei, Hao Feng, Shasha Wang, Xiao Cen, Shiyu Gao, Yaping Jiang, Jian Jiang, Qianming Chen, Yajie Tang, Yaling Tang, Xinhua Liang |
| Source: |
PLoS ONE, Vol 10, Iss 7, p e0133681 (2015) |
| Publisher Information: |
Public Library of Science (PLoS), 2015. |
| Publication Year: |
2015 |
| Collection: |
LCC:Medicine
LCC:Science |
| Subject Terms: |
Medicine, Science |
| More Details: |
Oropharyngeal squamous cell carcinoma (OPSCC) has been known to be a highly aggressive disease associated with human papilloma virus (HPV) infection. To investigate the relationship between HPV and chronic inflammation in oropharyngeal carcinogenesis, we collected 140 oral mucous fresh specimens including 50 OPSCC patients, 50 cancer in situ, 30 precancerous lesions, and 10 normal oral mucous. Our data demonstrated that there was a significantly higher proportion of severe chronic inflammation in dysplastic epithelia in comparison with that in normal tissues (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1932-6203 |
| Relation: |
http://europepmc.org/articles/PMC4507986?pdf=render; https://doaj.org/toc/1932-6203 |
| DOI: |
10.1371/journal.pone.0133681 |
| Access URL: |
https://doaj.org/article/d78e3a7afa434c8dbc64e7cae5298f83 |
| Accession Number: |
edsdoj.78e3a7afa434c8dbc64e7cae5298f83 |
| Database: |
Directory of Open Access Journals |
