An unrecognized undifferentiated tumor of the pancreas: a case report
Title: | An unrecognized undifferentiated tumor of the pancreas: a case report |
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Authors: | Chaoyu Pang, Zhiyao Fan, Peng Su, Hanxiang Zhan |
Source: | Journal of Pancreatology, Vol 6, Iss 4, Pp 225-227 (2023) |
Publisher Information: | Wolters Kluwer Health/LWW, 2023. |
Publication Year: | 2023 |
Collection: | LCC:Diseases of the digestive system. Gastroenterology |
Subject Terms: | Diseases of the digestive system. Gastroenterology, RC799-869 |
More Details: | SMARCA4-deficient tumors are gaining attention, and this type of tumor is highly malignant with a poor prognosis. The frequency of SMARCA4 deletion varies in different tumors. However, it has never been identified in the pancreas. A 67-year-old woman presented with upper abdominal pain lasting for half a month. Computed tomography indicated a space-occupying lesion in the head of the pancreas, considered a malignant tumor. Further Endoscopic ultrasound fine-needle aspiration was performed and reported as SMARCA4-deficient undifferentiated pancreatic tumor. The patient received no treatment and survived only two and a half months from diagnosis to death. We are the first to report SMARCA4-deficient pancreatic undifferentiated tumor in which this new tumor entity presents with poorer overall survival. We also summarized the advances of SMARCA4 in oncology and treatment. |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 2096-5664 00000000 |
Relation: | http://journals.lww.com/10.1097/JP9.0000000000000132; https://doaj.org/toc/2096-5664 |
DOI: | 10.1097/JP9.0000000000000132 |
Access URL: | https://doaj.org/article/78d469c45a2e4824bd4339564d3e1ec3 |
Accession Number: | edsdoj.78d469c45a2e4824bd4339564d3e1ec3 |
Database: | Directory of Open Access Journals |
ISSN: | 20965664 00000000 |
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DOI: | 10.1097/JP9.0000000000000132 |
Published in: | Journal of Pancreatology |
Language: | English |