| Title: |
Association between non-alcoholic fatty liver disease and progression of abdominal aortic aneurysm: a multicenter study |
| Authors: |
Ximing Wang, Jingxiang Sun, Na Chang, Menghan Liu, Shuai Zhang |
| Source: |
BMC Medical Imaging, Vol 25, Iss 1, Pp 1-9 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Medical technology |
| Subject Terms: |
Non-alcoholic fatty liver disease, Abdominal aortic aneurysm, Fatty liver, Multidetector computed tomography, Growth, Medical technology, R855-855.5 |
| More Details: |
Abstract Background The purpose of our study was to investigate the association between non-alcoholic fatty liver disease (NAFLD) and abdominal aortic aneurysms (AAA) progression using non-enhanced computed tomography (CT) and CT angiography (CTA). Methods Patients with AAA and age- and sex-matched healthy subjects who underwent abdominal CTA and non-enhanced CT examination between January 2015 and January 2023 from four hospitals were retrospectively analyzed. Patients with AAA were divided into progression (growth rate > 10 mL/year) and non-progression groups, as well as those with NAFLD and without NAFLD, based on abdominal CT results. The Kaplan-Meier and Cox regression were used to investigate the association between NAFLD and AAA progression. Results A total of 151 patients with AAA (mean age: 69.1 ± 10.5 years old, 133 men) were included, among which 66 patients (43.7%) had NAFLD. During a median of 10.7 months (6.0–76.0 months), 57 patients (37.7%) had AAA progression. The prevalence of NAFLD was significantly higher in the AAA group compared to the control group (43.7% vs. 31.1%, p = 0.024). Multivariable regression analysis revealed that the NAFLD was independently associated with AAA progression (HR, 4.28; 95% CI, 2.20–8.31; p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2342 |
| Relation: |
https://doaj.org/toc/1471-2342 |
| DOI: |
10.1186/s12880-025-01559-7 |
| Access URL: |
https://doaj.org/article/77d1d41e37aa4e8191f819b4ce895b70 |
| Accession Number: |
edsdoj.77d1d41e37aa4e8191f819b4ce895b70 |
| Database: |
Directory of Open Access Journals |
