Follow-up analysis and research of very low-risk and low-risk gastrointestinal stromal tumors after endoscopic resection

Bibliographic Details
Title: Follow-up analysis and research of very low-risk and low-risk gastrointestinal stromal tumors after endoscopic resection
Authors: Jiaxin Gao, Zide Liu, Xingxing Liu, Xu Shu, Yin Zhu, Youxiang Chen, Chunyan Zeng
Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Publisher Information: Nature Portfolio, 2024.
Publication Year: 2024
Collection: LCC:Medicine
LCC:Science
Subject Terms: Gastroenterology, Gastrointestinal stromal tumor, Endoscopic resection, Recurrence, Long-term outcomes, Medicine, Science
More Details: Abstract Currently, due to limited long-term evidence, there remains some controversy surrounding the recommended postoperative monitoring strategy for primary low-risk gastrointestinal stromal tumors (GISTs). This study recruited a total of 532 patients diagnosed with very low-risk and low-risk GISTs who underwent endoscopic resection from 2015 to 2021, including 460 very low-risk patients and 72 low-risk patients. Descriptive statistical analysis was used to evaluate the clinical and pathological characteristics of GIST patients, and Kaplan–Meier methods were employed for survival analysis. The results showed that the 5-year recurrence-free survival rates for very low-risk and low-risk patients were 98.5% and 95.9%, respectively. The 5-year disease-specific survival rates for both groups were 100%. Additionally, the 5-year overall survival rates were 99.7% for very low-risk patients and 100% for low-risk patients (P = 0.69). Therefore, it is suggested that routine follow-up monitoring, including endoscopic surveillance and imaging, may not be necessary for very low-risk and low-risk GISTs after endoscopic resection.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-024-68460-1
Access URL: https://doaj.org/article/ae774b46e9864d4c93a793756b6e5de0
Accession Number: edsdoj.774b46e9864d4c93a793756b6e5de0
Database: Directory of Open Access Journals
More Details
ISSN:20452322
DOI:10.1038/s41598-024-68460-1
Published in:Scientific Reports
Language:English