Bibliographic Details
| Title: |
Analysis of influencing factors of post-vaccination serologic testing in children exposed to hepatitis B virus in Tongzhou District， Beijing from 2020 to 2022 |
| Authors: |
WANG Ronghuan, BAO Zheng, HU Yue |
| Source: |
Shanghai yufang yixue, Vol 36, Iss 5, Pp 423-428 (2024) |
| Publisher Information: |
Shanghai Preventive Medicine Association, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
children exposed to hepatitis b virus （hbv）, post-vaccination serological test, hepatitis b surface antigen （hbsag） positive, hepatitis b vaccine, Medicine |
| More Details: |
ObjectiveTo explore the importance of post-vaccination serological testing （PVST） for children exposed to hepatitis B virus （HBV）， and analyze the factors affecting the progress of PVST.MethodsThe study focused on hepatitis B surface antigen （HBsAg）-positive pregnant women and their newborns residing in Tongzhou District， Beijing， who delivered at various obstetric institutions from January 1， 2020 to March 31， 2022. The obstetric institutions and community health service centers conducted follow-up visits 1 to 2 months after the children had received three doses of the hepatitis B vaccine （HepB）.ResultsThe vaccination rate of hepatitis B immunoglobulin （HBIg） was 100.00% （800/800）， with a successful PVST follow-up rate of 85.88% （687/800） in Tongzhou District. The initial non-response rate to immunization was 0.29% （2/687）， but successful immunization was achieved after re-immunization. The mother-to-infant transmission rate of hepatitis B was 0. Children who did not undergo PVST accounted for 14.13% （113/800）， with the main reasons being delays due to the COVID-19 pandemic， parents’ reluctance to allow venous blood collection due to the young age of the children， and loss to follow-up because children moved back to their parents’ place of origin. Logistic regression analysis showed that the proportion of PVST was higher among high-risk children （OR=30.009，P=0.001）， children with family residing in Beijing （OR=2.218，P=0.002）， and children whose mothers were |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Chinese |
| ISSN: |
1004-9231 |
| Relation: |
https://doaj.org/toc/1004-9231 |
| DOI: |
10.19428/j.cnki.sjpm.2024.23495 |
| Access URL: |
https://doaj.org/article/759b3724572d4813bd34b0e5f4bfccaf |
| Accession Number: |
edsdoj.759b3724572d4813bd34b0e5f4bfccaf |
| Database: |
Directory of Open Access Journals |
