Corticosteroid treatment for acute hydrocephalus in neurosarcoidosis: a case report

Bibliographic Details
Title: Corticosteroid treatment for acute hydrocephalus in neurosarcoidosis: a case report
Authors: Edoardo Dalmato Schilke, Giulia Remoli, Claudia Cutellé, Claudia Balducci, Diletta Cereda, Maria Letizia Fusco, Lucio Tremolizzo, Carlo Ferrarese, Ildebrando Appollonio, Maura Frigo
Source: Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-6 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Medicine
Subject Terms: Neuroimmunology, Neurosarcoidosis, Obstructive hydrocephalus, Neurosurgery in sarcoidosis, Medicine
More Details: Abstract Background Neurosarcoidosis occurs symptomatically in 5–10% of patients with sarcoidosis, and hydrocephalus is a rare complication of neurosarcoidosis, with either acute or subacute onset and presenting symptoms related to increased intracranial pressure. It represents a potentially fatal manifestation with a mortality rate of 22% (increased to 75% in case of coexistence of seizures) that requires a prompt initiation of treatment. High-dose intravenous corticosteroid treatment and neurosurgical treatment must be considered in all cases of neurosarcoidosis hydrocephalus. Case presentation Here we present a case of hydrocephalus in neurosarcoidosis, complicated by generalized seizures, in a 29-year-old Caucasian male patient treated with medical treatment only, with optimal response. Conclusion Since neurosurgery treatment can lead to severe complications, this case report underlines the possibility to undergo only medical treatment in selected cases. Further studies are needed to stratify patients and better identify those eligible for only medical approach.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1752-1947
Relation: https://doaj.org/toc/1752-1947
DOI: 10.1186/s13256-024-04359-9
Access URL: https://doaj.org/article/a756e0eeb56f45109212a18a21df8eed
Accession Number: edsdoj.756e0eeb56f45109212a18a21df8eed
Database: Directory of Open Access Journals
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More Details
ISSN:17521947
DOI:10.1186/s13256-024-04359-9
Published in:Journal of Medical Case Reports
Language:English