Comparative Analysis of COVID‐19 Severity and Mortality Among Vaccinated and Unvaccinated Individuals During the Delta Variant Surge in a Tertiary Care Center: A Cohort Study

Bibliographic Details
Title: Comparative Analysis of COVID‐19 Severity and Mortality Among Vaccinated and Unvaccinated Individuals During the Delta Variant Surge in a Tertiary Care Center: A Cohort Study
Authors: Fatemeh Hasani, Zahra Norouzi, Kimia Jazi, Gholamreza Roshandel, Alireza Norouzi
Source: Health Science Reports, Vol 8, Iss 1, Pp n/a-n/a (2025)
Publisher Information: Wiley, 2025.
Publication Year: 2025
Collection: LCC:Medicine
Subject Terms: Coronavirus disease 2019 (COVID‐19), delta variant, mortality, severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), tertiary care, vaccination, Medicine
More Details: ABSTRACT Background and Aims On March 11, 2020, the World Health Organization declared Coronavirus disease 2019 (COVID‐19) as a pandemic. The spread of the Delta variant of coronavirus started in June 2021 and accounted for the fifth peak of COVID‐19 in Iran in July 2021. According to reports from other countries, vaccination protects against severe diseases caused by COVID‐19, including the Delta variant. Studies have also shown that vaccination provides strong protection against SARS‐CoV‐2 infection, COVID‐19‐related hospitalization, and mortality. This retrospective cohort study was designed based on the medical care monitoring center database of Sayyad Shirazi Hospital. Methods COVID‐19 confirmed patients' data were extracted for this study from June 22, 2021, to September 22, 2021 including demographic characteristics, signs and symptoms, ICU admission, need for aggressive oxygen therapy, including intubation, mortality, and vaccination status. Results A total of 2962 patients were enrolled. Being vaccinated was associated with a 4.14‐fold increase in survival (adjusted OR = 4.14; 95% CI: 2.22–7.69; p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2398-8835
Relation: https://doaj.org/toc/2398-8835
DOI: 10.1002/hsr2.70346
Access URL: https://doaj.org/article/74c10507d3234d55b83f6a5953b0859a
Accession Number: edsdoj.74c10507d3234d55b83f6a5953b0859a
Database: Directory of Open Access Journals
More Details
ISSN:23988835
DOI:10.1002/hsr2.70346
Published in:Health Science Reports
Language:English