Bibliographic Details
| Title: |
Long-term outcomes of smoker and drinker with oesophageal squamous cell carcinoma after oesophagectomy: a large-scale propensity score matching analysis |
| Authors: |
Kun Liu, Yongtao Han, Ziwei Wang, Lin Peng, Kexun Li, Simiao Lu, Changding Li, Wenwu He, Kunyi Du, Chenghao Wang, Jialong Li, Yehan Zhou, Jiahua Lv, Qifeng Wang, Xuefeng Leng |
| Source: |
BMJ Open Gastroenterology, Vol 11, Iss 1 (2024) |
| Publisher Information: |
BMJ Publishing Group, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Diseases of the digestive system. Gastroenterology |
| Subject Terms: |
Diseases of the digestive system. Gastroenterology, RC799-869 |
| More Details: |
Background Oesophageal squamous cell carcinoma (OSCC) poses a considerable health burden, particularly in regions such as East Asia. This study aims to investigate the long-term outcomes of OSCC patients who are smokers and drinkers.Materials and methods In this retrospective analysis, data from Sichuan Cancer Hospital and Institute Esophageal Cancer Case Management Database between January 2010 and December 2017 were examined. Patients were categorised into different groups based on their smoking and alcohol consumption history: None, Smoker, Non-Smoker, Smoke-Only, Drinker, Non-Drinker, Drinker-Only, and Both. Survival outcomes were compared between the groups using Kaplan-Meier analysis and propensity score matching (PSM). The primary outcome was overall survival (OS), measured from surgery to death or last follow-up in April 2022.Results The OS median was 45.4 months for all patients after oesophagectomy. Smokers had a significantly lower median OS of 36.6 months compared with Non-Smokers with 66.2 months (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2054-4774 |
| Relation: |
https://bmjopengastro.bmj.com/content/11/1/e001452.full; https://doaj.org/toc/2054-4774 |
| DOI: |
10.1136/bmjgast-2024-001452 |
| Access URL: |
https://doaj.org/article/748f42f28ef74e9db4e5643e2fe3a897 |
| Accession Number: |
edsdoj.748f42f28ef74e9db4e5643e2fe3a897 |
| Database: |
Directory of Open Access Journals |
