Bibliographic Details
| Title: |
Annular elastolytic giant cell granuloma: An atypical presentation |
| Authors: |
Vinitha Gopalakrishnan, Thonduparambil Pappan Thankappan, Gopalan Sulochana |
| Source: |
Indian Journal of Dermatopathology and Diagnostic Dermatology, Vol 5, Iss 1, Pp 51-53 (2018) |
| Publisher Information: |
Wolters Kluwer Medknow Publications, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Dermatology |
| Subject Terms: |
Actinic granuloma, elastophagocytosis, papular annular elastolytic giant cell granuloma, Dermatology, RL1-803 |
| More Details: |
Annular elastolytic giant cell granuloma is a rare granulomatous disease with unknown pathogenesis. It clinically presents as single or multiple well-defined erythematous annular arciform serpiginous polycyclic plaque with indurated elevated borders and central atrophy in sun-exposed areas. It is found to have a causal association with conditions such as diabetes mellitus, T-cell leukemia, CD4 lymphoma, cutaneous amyloidosis, squamous cell carcinoma lung, sarcoidosis, and monoclonal gammopathy. On histopathology, characteristic “elastophagocytosis” of dermal elastic fibers by the multinucleated giant cells is seen. The presence of horizontally oriented fragmented elastic fibers is characteristic. There is no necrobiosis or mucin deposition, thus differentiating from granuloma annulare. We herein report a case of elderly male with type 2 diabetes mellitus who presented with asymptomatic multiple discrete erythematous shiny dome-shaped papules over anterior chest, abdomen, and back of 2-month duration. The diagnosis was confirmed by biopsy and thorough workup for associations was done. This case is reported due to the rarity of the disease, the atypical presentation, and the characteristic histopathology which lead to the diagnosis. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2349-6029 |
| Relation: |
http://www.ijdpdd.com/article.asp?issn=2349-6029;year=2018;volume=5;issue=1;spage=51;epage=53;aulast=Gopalakrishnan; https://doaj.org/toc/2349-6029 |
| DOI: |
10.4103/ijdpdd.ijdpdd_42_17 |
| Access URL: |
https://doaj.org/article/7407a6a4cdb249f898d8fb38ff09a229 |
| Accession Number: |
edsdoj.7407a6a4cdb249f898d8fb38ff09a229 |
| Database: |
Directory of Open Access Journals |
