The correlation between coronary artery, aortic, and mitral valve calcification in patients with coronary atherosclerosis

Bibliographic Details
Title: The correlation between coronary artery, aortic, and mitral valve calcification in patients with coronary atherosclerosis
Authors: Benedicta Mutiara Suwita, Indrati Suroyo, Lusiani Rusdi, Joedo Prihartono
Source: The Egyptian Journal of Radiology and Nuclear Medicine, Vol 54, Iss 1, Pp 1-7 (2023)
Publisher Information: SpringerOpen, 2023.
Publication Year: 2023
Collection: LCC:Medical physics. Medical radiology. Nuclear medicine
Subject Terms: Aortic valve, Atherosclerosis, Calcification, Calcium score, Computed tomography, Coronary artery, Medical physics. Medical radiology. Nuclear medicine, R895-920
More Details: Abstract Background Atherosclerosis is the underlying process causing coronary artery calcification. Pathophysiology of aortic and mitral valve calcification has several similarities with coronary atherosclerosis, but their correlation has not been clear, especially in patients with coronary atherosclerosis. Purpose This study aims to investigate the correlation between the calcium score of the coronary arteries, aortic, and mitral valves in patients with coronary atherosclerosis. Methods This was a cross-sectional, correlation study. Stratified randomization was done based on the coronary artery calcium score category. The calcium score was calculated using Agatston technique. Statistical tests were done to look for the correlations between the coronary artery and aortic valve calcium score, coronary artery and mitral valve calcium score, as well as coronary artery and aortic + mitral valve calcium score. Results There are ninety-seven subjects (coronary calcium score “mild” 34 subjects, “moderate” 30 subjects, “severe” 33 subjects) with a mean age of 63.85 (± 9.80) years old. The median coronary artery calcium score was 158.7 (Agatston Unit (AU; 1–3917.7), aortic valve 12.6 AU (0–3747), and mitral valve 0.1 AU (0–1247.5 AU). There was a very weak correlation between coronary artery calcium score with aortic, mitral, and aortic + mitral valve calcium score. Conclusions There was no statistically significant correlation between the calcium score of the coronary artery and the calcium score of the aortic valve, as well as the calcium score of the mitral valve in patients with coronary atherosclerosis. However, the secondary analysis showed a correlation between them varied depending on the severity of coronary artery calcification, which could shed light on a better understanding of the atherosclerotic process in the coronary artery, aortic, and mitral valve.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2090-4762
Relation: https://doaj.org/toc/2090-4762
DOI: 10.1186/s43055-023-01053-6
Access URL: https://doaj.org/article/73fdb1ee5b78425eac2a90411dc552fe
Accession Number: edsdoj.73fdb1ee5b78425eac2a90411dc552fe
Database: Directory of Open Access Journals
More Details
ISSN:20904762
DOI:10.1186/s43055-023-01053-6
Published in:The Egyptian Journal of Radiology and Nuclear Medicine
Language:English