Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018–2019
| Title: | Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018–2019 |
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| Authors: | Laura E. Nabarro, Colin S. Brown, Sooria Balasegaram, Valérie Decraene, James Elston, Smita Kapadia, Pauline Harrington, Peter Hoffman, Rachel Mearkle, Bharat Patel, Derren Ready, Esther Robinson, Theresa Lamagni |
| Source: | Emerging Infectious Diseases, Vol 28, Iss 5, Pp 915-923 (2022) |
| Publisher Information: | Centers for Disease Control and Prevention, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Infectious and parasitic diseases |
| Subject Terms: | Group A Streptococcus, Bacteria, Streptococci, Streptococcus pyogenes, public health, long-term care, Medicine, Infectious and parasitic diseases, RC109-216 |
| More Details: | Healthcare-associated invasive group A Streptococcus (iGAS) outbreaks are common worldwide, but only England has reported outbreaks associated with home healthcare (HHC). We describe 10 outbreaks during 2018–2019 in England. A total of 96 iGAS cases (range 2–39 per outbreak) and 28 deaths (case-fatality rate 29%) occurred. Outbreak duration ranged from 3–517 days; median time between sequential cases was 20.5 days (range 1–225 days). Outbreak identification was difficult, but emm typing and whole-genome sequencing improved detection. Network analyses indicated multiple potential transmission routes. Screening of 366 HHC workers from 9 outbreaks identified group A Streptococcus carriage in just 1 worker. Outbreak control required multiple interventions, including improved infection control, equipment decontamination, and antimicrobial prophylaxis for staff. Transmission routes and effective interventions are not yet clear, and iGAS outbreaks likely are underrecognized. To improve patient safety and reduce deaths, public health agencies should be aware of HHC-associated iGAS. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/28/5/21-1497_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid2805.211497 |
| Access URL: | https://doaj.org/article/ccd73da7003c40fd90553aca59e2bef2 |
| Accession Number: | edsdoj.73da7003c40fd90553aca59e2bef2 |
| Database: | Directory of Open Access Journals |
| ISSN: | 10806040 10806059 |
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| DOI: | 10.3201/eid2805.211497 |
| Published in: | Emerging Infectious Diseases |
| Language: | English |