Acute Chest Pain as an Infusion Reaction to Vedolizumab

Bibliographic Details
Title: Acute Chest Pain as an Infusion Reaction to Vedolizumab
Authors: Asaf Levartovsky, Miri Yavzori, Ella Fudim, Uri Kopylov, Shomron Ben-Horin, Bella Ungar
Source: Case Reports in Gastroenterology, Vol 16, Iss 2, Pp 430-434 (2022)
Publisher Information: Karger Publishers, 2022.
Publication Year: 2022
Collection: LCC:Diseases of the digestive system. Gastroenterology
Subject Terms: vedolizumab, adverse reaction, chest pain, Diseases of the digestive system. Gastroenterology, RC799-869
More Details: Vedolizumab-associated adverse effects, including infusion reactions, are generally uncommon. Less than 5% of patients experience an infusion-related reaction. We report a 67-year-old male with ulcerative colitis under prolonged maintenance therapy who presented with recurring chest pain occurring immediately after consecutive vedolizumab infusions. Medical workup of possible etiologies for chest pain were investigated and excluded. Vedolizumab drug trough levels were negative, accompanied by high detectable levels of anti-vedolizumab antibodies. These findings demonstrate an uncommon case of an infusion reaction to vedolizumab infusion.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1662-0631
Relation: https://www.karger.com/Article/FullText/525404; https://doaj.org/toc/1662-0631
DOI: 10.1159/000525404
Access URL: https://doaj.org/article/725fe4005df8409da684e611858f6920
Accession Number: edsdoj.725fe4005df8409da684e611858f6920
Database: Directory of Open Access Journals
More Details
ISSN:16620631
DOI:10.1159/000525404
Published in:Case Reports in Gastroenterology
Language:English