Academic Journal
Early-onset prosthetic valve endocarditis definition revisited: Prospective study and literature review
| Title: | Early-onset prosthetic valve endocarditis definition revisited: Prospective study and literature review |
|---|---|
| Authors: | Rinaldo Focaccia Siciliano, Bruno Azevedo Randi, Danielle Menosi Gualandro, Roney Orismar Sampaio, Márcio Sommer Bittencourt, Christian Emmanuel da Silva Pelaes, Alfredo José Mansur, Pablo Maria Alberto Pomerantzeff, Flávio Tarasoutchi, Tânia Mara Varejão Strabelli |
| Source: | International Journal of Infectious Diseases, Vol 67, Iss C, Pp 3-6 (2018) |
| Publisher Information: | Elsevier, 2018. |
| Publication Year: | 2018 |
| Collection: | LCC:Infectious and parasitic diseases |
| Subject Terms: | Infective endocarditis, Antibacterial agent, Heart valve prostheses, Infectious and parasitic diseases, RC109-216 |
| More Details: | Objective: To determine the annual incidence of prosthetic valve endocarditis (PVE) and to evaluate its current classification based on the epidemiological distribution of agents identified and their sensitivity profiles. Methods: Consecutive cases of PVE occurring within the first year of valve surgery during the period 1997–2014 were included in this prospective cohort study. Incidence, demographic, clinical, microbiological, and in-hospital mortality data of these PVE patients were recorded. Results: One hundred and seventy-two cases of PVE were included, and the global annual incidence of PVE was 1.7%. Most PVE cases occurred within 120 days after surgery (76.7%). After this period, there was a reduction in resistant microorganisms (64.4% vs. 32.3%, respectively; p = 0.007) and an increase in the incidence of Streptococcus spp (1.9% vs. 23.5%; p = 0.007). A literature review revealed 646 cases of PVE with an identified etiology, of which 264 (41%) were caused by coagulase-negative staphylococci and 43 (7%) by Streptococcus spp. This is in agreement with the current study findings. Conclusions: Most PVE cases occurred within 120 days after valve surgery, and the same etiological agents were identified in this period. The current cut-off level of 365 days for the classification of early-onset PVE should be revisited. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1201-9712 1878-3511 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S120197121730228X; https://doaj.org/toc/1201-9712; https://doaj.org/toc/1878-3511 |
| DOI: | 10.1016/j.ijid.2017.09.004 |
| Access URL: | https://doaj.org/article/d7118ad8724e4622bdeca5d55c2f0fc4 |
| Accession Number: | edsdoj.7118ad8724e4622bdeca5d55c2f0fc4 |
| Database: | Directory of Open Access Journals |
| ISSN: | 12019712 18783511 |
|---|---|
| DOI: | 10.1016/j.ijid.2017.09.004 |
| Published in: | International Journal of Infectious Diseases |
| Language: | English |