Features of acute megakaryoblastic leukemia diagnosis in a child with Down syndrome
| Title: | Features of acute megakaryoblastic leukemia diagnosis in a child with Down syndrome |
|---|---|
| Authors: | N. K. Guskova, O. N. Selyutina, I. B. Lysenko, Yu. Yu. Kozel, O. V. Kozyuk, V. V. Dmitrieva, M. A. Baranenkova, A. S. Nozdricheva |
| Source: | Онкогематология, Vol 18, Iss 1, Pp 31-38 (2023) |
| Publisher Information: | ABV-press, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Diseases of the blood and blood-forming organs |
| Subject Terms: | down syndrome, acute myeloid leukemia, acute megakaryoblastic leukemia, morphological examination of the bone marrow, flow cytometry, Diseases of the blood and blood-forming organs, RC633-647.5 |
| More Details: | We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia in a child with Down syndrome aggravated by multiple comorbidities. In this case, a comprehensive assessment of clinical data, the results of an automatic complete blood count with a detailed interpretation of the entire range of parameters, as well as morphological and immunophenotypic bone marrow examination using an extended panel of monoclonal antibodies played a key role in the diagnosis. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | Russian |
| ISSN: | 1818-8346 2413-4023 |
| Relation: | https://oncohematology.abvpress.ru/ongm/article/view/796; https://doaj.org/toc/1818-8346; https://doaj.org/toc/2413-4023 |
| DOI: | 10.17650/1818-8346-2023-18-1-31-38 |
| Access URL: | https://doaj.org/article/70b5856df3b546e9977e6ba9a8bb3cbe |
| Accession Number: | edsdoj.70b5856df3b546e9977e6ba9a8bb3cbe |
| Database: | Directory of Open Access Journals |
| ISSN: | 18188346 24134023 |
|---|---|
| DOI: | 10.17650/1818-8346-2023-18-1-31-38 |
| Published in: | Онкогематология |
| Language: | Russian |