Bibliographic Details
| Title: |
Shift in risk factors for mortality by period of the bloodstream infection timeline |
| Authors: |
Min Hyuk Choi, Dokyun Kim, Jihyun Kim, Young Goo Song, Seok Hoon Jeong |
| Source: |
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 97-106 (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Microbiology |
| Subject Terms: |
Bloodstream infection, Subsequent bloodstream infection, Risk factors, Mortality, Vancomycin-resistant enterococci, Microbiology, QR1-502 |
| More Details: |
Background: This study was designed to determine changes in risk factors on the prognosis of patients during each period of the bloodstream infection (BSI) timeline. Methods: Through an integrated study of multivariable regressions with machine learning techniques, the risk factors for mortality during each period of BSI were analyzed. Results: A total of 302,303 inpatients who underwent blood cultures during 2011–2021 were enrolled. More than 8 % of BSI cases progressed to subsequent BSI, and risk factors were identified as gut colonization with vancomycin-resistant enterococci (aOR 1.82; 95 % CI 1.47–2.24), intensive care unit admission (aOR 3.37; 95 % CI 3.35–4.28), and current cancer chemotherapy (aOR 1.54; 95 % CI 1.36–1.74). The mean SOFA score of the deceased patients during the first 7 days was 10.6 (SD 4.3), which was significantly higher than those on days 8–30 (7.0 ± 4.2) and after Day 30 (4.0 ± 3.5). BSIs caused by Acinetobacter baumannii and Candida albicans were more likely to result in deaths of patients for all time periods (all, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1684-1182 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1684118223002141; https://doaj.org/toc/1684-1182 |
| DOI: |
10.1016/j.jmii.2023.11.008 |
| Access URL: |
https://doaj.org/article/6f521e601b2646d48e54e04aa6ed6ca4 |
| Accession Number: |
edsdoj.6f521e601b2646d48e54e04aa6ed6ca4 |
| Database: |
Directory of Open Access Journals |
