Recurrent Acute Coronary Syndromes in a Patient with Idiopathic Thrombocytopenic Purpura

Bibliographic Details
Title: Recurrent Acute Coronary Syndromes in a Patient with Idiopathic Thrombocytopenic Purpura
Authors: Nikolaos Iakovis, Andrew Xanthopoulos, Aikaterini Chamaidi, Michail Papamichalis, Apostolos Dimos, Filippos Triposkiadis, John Skoularigis
Source: Case Reports in Cardiology, Vol 2020 (2020)
Publisher Information: Hindawi Limited, 2020.
Publication Year: 2020
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: A 53-year-old man was admitted to a peripheral hospital with the diagnosis of acute myocardial infarction without ST elevation. Due to the concomitant presence of first-diagnosed thrombocytopenia (platelet count 50.000/μL), it was decided to be treated conservatively with clopidogrel. Five days later, he developed an acute myocardial infarction with ST elevation (STEMI) and was transferred to our department for primary percutaneous coronary intervention (PCI). Coronary angiography revealed three-vessel disease. The left anterior descending lesion was considered culprit, and PCI was successfully performed using a drug-eluting balloon. This approach was considered safer due to the risk of intolerance of prolonged dual antiplatelet therapy in case of stent implantation. Indeed, four days later, aspirin was discontinued, and the patient remained only on clopidogrel due to a platelet fall. Meanwhile, idiopathic thrombocytopenic purpura (ITP) was diagnosed by hematology consultation, and specific ITP treatment was initiated. Seven days following the procedure, the patient was transferred to the Hematology clinic, where a continuous rise of platelet count up to 115.000/μL while on clopidogrel was observed, and he was discharged from the hospital asymptomatic. Unfortunately, twenty days later, the patient died of a lung infection. In ITP patients with STEMI, primary PCI with drug-eluting balloon angioplasty may be a reasonable approach.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2090-6404
2090-6412
Relation: https://doaj.org/toc/2090-6404; https://doaj.org/toc/2090-6412
DOI: 10.1155/2020/6738348
Access URL: https://doaj.org/article/6f3a3b5c0f894d518a0b43b2be8f7262
Accession Number: edsdoj.6f3a3b5c0f894d518a0b43b2be8f7262
Database: Directory of Open Access Journals
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More Details
ISSN:20906404
20906412
DOI:10.1155/2020/6738348
Published in:Case Reports in Cardiology
Language:English