Bibliographic Details
| Title: |
Clinical Characteristics, Prognostic Factors and Therapeutic Strategies in Gastric Cancer Patients With Bone Metastasis: A Retrospective Analysis |
| Authors: |
Shiji Ren, Yutao Wei, Wenqi Liu, Yipeng Zhang, Yue Wang, Ju Yang, Baorui Liu, Tao Shi, Jia Wei |
| Source: |
Cancer Medicine, Vol 14, Iss 6, Pp n/a-n/a (2025) |
| Publisher Information: |
Wiley, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
bone metastasis, gastric cancer, immunotherapy, poorly cohesive, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
ABSTRACT Background Bone metastases are highly refractory and are associated with extremely poor survival. Despite the increasing incidence of bone metastasis in gastric cancer (GC), comprehensive analyses regarding the clinicopathological features, prognosis, and treatment of bone‐metastatic GC remain limited. Methods We obtained data from 120 bone‐metastatic GC patients from Nanjing Drum Tower Hospital and 36,139 GC patients from the SEER database. Chi‐square and Mann–Whitney U‐tests evaluated clinicopathological features, while Cox models identified prognostic factors. Kaplan–Meier curves and forest plots assessed the effects of different treatment strategies on overall survival after bone metastasis (OS‐BM). Results Among 120 bone‐metastatic GC patients, 55 (45.83%) were diagnosed with poorly cohesive gastric carcinoma (PCC). The higher incidence of bone metastasis was also observed in SRCC patients from the SEER database (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2045-7634 |
| Relation: |
https://doaj.org/toc/2045-7634 |
| DOI: |
10.1002/cam4.70781 |
| Access URL: |
https://doaj.org/article/c6f140e0fd264b3f9ab77bbedbbb9e2b |
| Accession Number: |
edsdoj.6f140e0fd264b3f9ab77bbedbbb9e2b |
| Database: |
Directory of Open Access Journals |
