Bibliographic Details
| Title: |
Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| Authors: |
Elena Cortés-Vicente, Daniel Guisado-Alonso, Raquel Delgado-Mederos, Pol Camps-Renom, Luis Prats-Sánchez, Alejandro Martínez-Domeño, Joan Martí-Fàbregas |
| Source: |
Frontiers in Neurology, Vol 10 (2019) |
| Publisher Information: |
Frontiers Media S.A., 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
stroke, dehydration, urea, creatinine, prognosis, risk factors, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Objective: To determine the frequency, risk factors, and impact on the outcome of dehydration after stroke.Methods: In this cross-sectional observational study, we included prospectively and consecutively patients with ischemic and hemorrhagic stroke. The serum Urea/Creatinine ratio (U/C) was calculated at admission and 3 days after the stroke. Dehydration was defined as U/C>80. Patients were treated in accordance with the standard local hydration protocol. Demographic and clinical data were collected. Neurological severity was evaluated at admission according to the NIHSS score; functional outcome was assessed with the modified Rankin scale score (mRS) at discharge and 3 months after the stroke. Unfavorable outcome was defined as mRS > 2.Results: We evaluated 203 patients; 78.8% presented an ischemic stroke and 21.2% a hemorrhagic stroke. The mean age was 73.4 years ±12.9; 51.7% were men. Dehydration was detected in 18 patients (8.9%), nine patients at admission (4.5%), and nine patients (4.5%) at 3 days after the stroke. Female sex (OR 3.62, 95%CI 1.13–11.58, p = 0.03) and older age (OR 1.05, 95%CI 1–1.11, p = 0.048) were associated with a higher risk of dehydration. Dehydration was significantly associated with an unfavorable outcome at discharge (OR 5.16, 95%CI 1.45–18.25, p = 0.011), but the association was not significant at 3 months (OR 2.95, 95%CI 0.83–10.48, p = 0.095).Conclusion: Dehydration is a treatable risk factor of a poor functional outcome after stroke that is present in 9% of patients. Females and elders present a higher risk of dehydration. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-2295 |
| Relation: |
https://www.frontiersin.org/article/10.3389/fneur.2019.00305/full; https://doaj.org/toc/1664-2295 |
| DOI: |
10.3389/fneur.2019.00305 |
| Access URL: |
https://doaj.org/article/6eb090fb63914e7fbb7a05174d296928 |
| Accession Number: |
edsdoj.6eb090fb63914e7fbb7a05174d296928 |
| Database: |
Directory of Open Access Journals |
