Bibliographic Details
Title: |
Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations |
Authors: |
Samuel W. Brady, Yanling Liu, Xiaotu Ma, Alexander M. Gout, Kohei Hagiwara, Xin Zhou, Jian Wang, Michael Macias, Xiaolong Chen, John Easton, Heather L. Mulder, Michael Rusch, Lu Wang, Joy Nakitandwe, Shaohua Lei, Eric M. Davis, Arlene Naranjo, Cheng Cheng, John M. Maris, James R. Downing, Nai-Kong V. Cheung, Michael D. Hogarty, Michael A. Dyer, Jinghui Zhang |
Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
Publisher Information: |
Nature Portfolio, 2020. |
Publication Year: |
2020 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Genomic analysis of neuroblastoma has revealed important disease etiology. In this study, the authors assembled whole genome, exome and transcriptome data from over 700 neuroblastomas and identified molecular signatures correlated with age, and rare, potentially targetable variants overlooked in smaller cohorts. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-020-18987-4 |
Access URL: |
https://doaj.org/article/6d1ddb168abf4a2ea4dc3f42ec5b32a2 |
Accession Number: |
edsdoj.6d1ddb168abf4a2ea4dc3f42ec5b32a2 |
Database: |
Directory of Open Access Journals |