Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

Bibliographic Details
Title: Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations
Authors: Samuel W. Brady, Yanling Liu, Xiaotu Ma, Alexander M. Gout, Kohei Hagiwara, Xin Zhou, Jian Wang, Michael Macias, Xiaolong Chen, John Easton, Heather L. Mulder, Michael Rusch, Lu Wang, Joy Nakitandwe, Shaohua Lei, Eric M. Davis, Arlene Naranjo, Cheng Cheng, John M. Maris, James R. Downing, Nai-Kong V. Cheung, Michael D. Hogarty, Michael A. Dyer, Jinghui Zhang
Source: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Publisher Information: Nature Portfolio, 2020.
Publication Year: 2020
Collection: LCC:Science
Subject Terms: Science
More Details: Genomic analysis of neuroblastoma has revealed important disease etiology. In this study, the authors assembled whole genome, exome and transcriptome data from over 700 neuroblastomas and identified molecular signatures correlated with age, and rare, potentially targetable variants overlooked in smaller cohorts.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-020-18987-4
Access URL: https://doaj.org/article/6d1ddb168abf4a2ea4dc3f42ec5b32a2
Accession Number: edsdoj.6d1ddb168abf4a2ea4dc3f42ec5b32a2
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-020-18987-4
Published in:Nature Communications
Language:English