Impact of Antithrombin Activity Levels Following Recombinant Antithrombin Gamma Therapy in Patients with Sepsis-Induced Disseminated Intravascular Coagulation
| Title: | Impact of Antithrombin Activity Levels Following Recombinant Antithrombin Gamma Therapy in Patients with Sepsis-Induced Disseminated Intravascular Coagulation |
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| Authors: | Tomohiko Akahoshi MD, PhD, Noriyuki Kaku MD, PhD, Yuji Shono MD, PhD, Yuzo Yamamoto MD, PhD, Keita Takahashi MD, PhD, Takeshi Iyonaga MD, PhD, Kenta Momii MD, Masaaki Nishihara MD, PhD, Jun Maki MD, PhD, Kentaro Tokuda MD, PhD, Ken Yamaura MD, PhD |
| Source: | Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022) |
| Publisher Information: | SAGE Publishing, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: | Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: | Recombinant antithrombin gamma (rAT) is reported as an effective drug for patients with disseminated intravascular coagulation (DIC) in Japan. As the appropriate dose and targeted AT activity remain unknown, this study aimed to determine these aspects for sepsis-induced DIC. Thirty-one patients with septic shock and DIC with AT levels |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1938-2723 10760296 |
| Relation: | https://doaj.org/toc/1938-2723 |
| DOI: | 10.1177/10760296221135790 |
| Access URL: | https://doaj.org/article/6ceaab12e00a4186a01dbda1ab35f50d |
| Accession Number: | edsdoj.6ceaab12e00a4186a01dbda1ab35f50d |
| Database: | Directory of Open Access Journals |
| ISSN: | 19382723 10760296 |
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| DOI: | 10.1177/10760296221135790 |
| Published in: | Clinical and Applied Thrombosis/Hemostasis |
| Language: | English |