Bibliographic Details
| Title: |
The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure |
| Authors: |
Robert E. Turnbull, Louise Fairall, Almutasem Saleh, Emma Kelsall, Kyle L. Morris, T. J. Ragan, Christos G. Savva, Aditya Chandru, Christopher J. Millard, Olga V. Makarova, Corinne J. Smith, Alan M. Roseman, Andrew M. Fry, Shaun M. Cowley, John W. R. Schwabe |
| Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
| Publisher Information: |
Nature Portfolio, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
The MiDAC complex recruits class I histone deacetylases to chromatin but little is known about its precise structure and function. Here, the authors explore the role of MiDAC in the cell cycle and during mouse embryogenesis, and present cryoEM structures that provide insight into MiDAC’s mode of assembly. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-020-17078-8 |
| Access URL: |
https://doaj.org/article/6a71d260306a424c936ce21edc133482 |
| Accession Number: |
edsdoj.6a71d260306a424c936ce21edc133482 |
| Database: |
Directory of Open Access Journals |
